PDE6C Polyclonal antibody, PBS Only

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  WB analysis of Y79 using 55183-1-AP (same clone as 55183-1-PBS)

  Y79 cells were subjected to SDS PAGE followed by western blot with 55183-1-AP (PDE6C antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55183-1-PBS in a different storage buffer formulation.

PDE6C Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55183-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

55183-1-PBS targets PDE6C in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: phosphodiesterase 6C, cGMP-specific, cone, alpha prime
• Calculated Molecular Weight: 99 kDa
• Observed Molecular Weight: 52 kDa, 99 kDa
• GenBank Accession Number: NM_006204
• Gene Symbol: PDE6C
• Gene ID (NCBI): 5146
• RRID: AB_10837359
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P51160
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

PDE6C, also named as PDEA2, belongs to the cyclic nucleotide phosphodiesterase family. It catalyze the reaction: Guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. Defects in PDE6C are the cause of cone dystrophy type 4 (COD4). Mutations in the PDE6C gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase as a cause of autosomal recessive achromatopsia.(PMID:19887631) This antibody is specific to PDE6C.