PPP1R17 Polyclonal antibody
PPP1R17 Polyclonal Antibody for WB, IF, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, mouse, rat
Applications
WB, IF, ELISA
Conjugate
Unconjugated
Cat no : 27976-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | mouse cerebellum tissue, rat cerebellum tissue |
Positive IF detected in | U2OS cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:5000-1:50000 |
Immunofluorescence (IF) | IF : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
27976-1-AP targets PPP1R17 in WB, IF, ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PPP1R17 fusion protein Ag15187 |
Full Name | chromosome 7 open reading frame 16 |
Calculated Molecular Weight | 155 aa, 18 kDa |
Observed Molecular Weight | 20-30 kDa |
GenBank Accession Number | BC028094 |
Gene Symbol | C7orf16 |
Gene ID (NCBI) | 10842 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
PPP1R17, an endogenous substrate for cGMP-dependent protein kinase, exists almost exclusively in cerebellar Purkinje cells, where it is possibly involved in the induction of long-term depression (PMID: 10051666). PPP1R17 inhibits phosphatase activities of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) complexes. Allelic variants increase susceptibility to hypercholesterolemia (PMID: 12955585).
Protocols
Product Specific Protocols | |
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WB protocol for PPP1R17 antibody 27976-1-AP | Download protocol |
IF protocol for PPP1R17 antibody 27976-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |