peroxiredoxin 2 Antibody 16 Publications

Rabbit Polyclonal| Catalog number: 10545-2-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 30 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, human brain tissue, SMMC-7721 cells, HepG2 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human ovary tumor tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
peroxiredoxin 2

Calculated molecular weight:
22 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PRDX2

Synonyms
NKEF B, NKEFB, peroxiredoxin 2, PRDX2, PRP, PRX II, PRX2, PRXII, TDPX1, Thioredoxin peroxidase 1, TSA
Background

PRDX2, also named as TSA, PRP, NKEFB and TDPX1, belongs to the ahpC/TSA family. It is known to act as an antioxidant enzyme whose main function is H2O2 reduction in cells. PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. It may play an important role in eliminating peroxides generated during metabolism. PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. PRDX2 actions may be related to the expression of NFKB and IKB.(PMID:21248284)


Back
to top