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  • KD/KO Validated

PRDX4 Polyclonal antibody

PRDX4 Polyclonal Antibody for FC, IF, IHC, IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 10703-1-AP


Antioxidant enzyme AOE372, AOE37 2, peroxiredoxin 4, Peroxiredoxin IV, PRDX4, PRX 4, Prx IV, Thioredoxin peroxidase AO372

Tested Applications

Positive WB detected inA375 cells, Jurkat cells, HEK-293 cells, HepG2 cells
Positive IP detected inHepG2 cells
Positive IHC detected inhuman colon cancer tissue, human pancreas cancer tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells
Positive FC detected inHepG2 cells
Planning an IF experiment? We recommend our CoraLite®650 conjugated versions of this antibody.

Recommended dilution

Western Blot (WB)WB : 1:1000-1:8000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

10703-1-AP targets PRDX4 in WB, IP, IHC, IF, FC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PRDX4 fusion protein Ag1177
Full Name peroxiredoxin 4
Calculated molecular weight 31 kDa
Observed molecular weight 30 kDa
GenBank accession numberBC007107
Gene symbol PRDX4
Gene ID (NCBI) 10549
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

PRDX4 (Peroxiredoxin-4) is also named as AOE37-2, Prx-IV and belongs to the AhpC/TSA family. PRDX4 is associated with acrosome formation during rat spermatogenesis and has a protective role in the male reproductive tract, because the phenotype of mice lacking this isoform includes testicular atrophy and increased sperm DNA damage (PMID:20864641). It is initially synthesized as a membrane-binding 31-kDa protein and processed into a 27-kDa secretory form and is discarded with the residual bodies (PMID:19208552). PRDX4 is a pentamer of dimers (PMID:23025503). This antibody is specific to PRDX4.


Product Specific Protocols
WB protocol for PRDX4 antibody 10703-1-APDownload protocol
IHC protocol for PRDX4 antibody 10703-1-APDownload protocol
IF protocol for PRDX4 antibody 10703-1-APDownload protocol
IP protocol for PRDX4 antibody 10703-1-APDownload protocol
FC protocol for PRDX4 antibody 10703-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Br J Pharmacol

Luteolin ameliorates rat myocardial ischemia-reperfusion injury through peroxiredoxin II activation.

Authors - Bo Wei

Hepatobiliary Pancreat Dis Int

Comparative proteomic analysis of differentially expressed proteins in human pancreatic cancer tissue.

Authors - Chen Jian-Hua JH

Can J Physiol Pharmacol

Galectin-3 inhibition attenuates doxorubicin-induced cardiac dysfunction by upregulating the expression of peroxiredoxin-4.

Authors - Yunpeng Tian
  • KD Validated

Transl Androl Urol

Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks.

Authors - Julian Cornelius

Proteomics Clin Appl

Quantitative proteomic analysis of a paired human liver healthy versus carcinoma cell lines with the same genetic background to identify potential hepatocellular carcinoma markers.

Authors - Bao Huimin H

Clin Immunol

Peroxiredoxin 4 regulates tumor-cell-like characteristics of fibroblast-like synoviocytes in rheumatoid arthritis through PI3k/Akt signaling pathway.

Authors - Yirixiati Aihaiti