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Secretogranin III Polyclonal antibody

Secretogranin III Polyclonal Antibody for IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse and More (1)





Cat no : 10954-1-AP


SCG3, Secretogranin 3, secretogranin III, SGIII

Tested Applications

Positive IHC detected inmouse pancreas tissue, human pancreas cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inmouse pancreas tissue

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10954-1-AP targets Secretogranin III in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Secretogranin III fusion protein Ag1397
Full Name secretogranin III
Calculated Molecular Weight 53 kDa
GenBank Accession NumberBC014539
Gene Symbol Secretogranin 3
Gene ID (NCBI) 29106
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Secretogranin III (SCG3), a member of the granin protein family, is expressed specifically in neuronal and endocrine cells. SCG3 was synthesized as a 61- or 63-kDa protein and processed to a 48-kDa form which, in turn, was partially cleaved to fragments of 28 and 20 kDa.


Product Specific Protocols
IHC protocol for Secretogranin III antibody 10954-1-APDownload protocol
IF protocol for Secretogranin III antibody 10954-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Exp Med

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.

Authors - Michelle E LeBlanc

Cancer Lett

The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells.

Authors - Yue Wang
  • KD Validated

Cereb Cortex

Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.

Authors - Paco Sonia S
human, mouseIHC

Brain Pathol

Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.

Authors - Virginia Plá

J Endocrinol

Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.

Authors - Hotta Kikuko K

Adv Sci (Weinh)

Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation.

Authors - Zhaohan Lin
  • KD Validated