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Secretogranin III Polyclonal antibody
Secretogranin III Polyclonal Antibody for IF, IHC, ELISA
Host / Isotype
Rabbit / IgG
human, mouse and More (1)
WB, IHC, IF, ELISA
Cat no : 10954-1-AP
Validation Data Gallery
|Positive IHC detected in||mouse pancreas tissue, human pancreas cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||mouse pancreas tissue|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 2 publications below|
|WB||See 4 publications below|
|IHC||See 4 publications below|
|IF||See 5 publications below|
10954-1-AP targets Secretogranin III in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Secretogranin III fusion protein Ag1397|
|Full Name||secretogranin III|
|Calculated molecular weight||53 kDa|
|GenBank accession number||BC014539|
|Gene ID (NCBI)||29106|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Secretogranin III (SCG3), a member of the granin protein family, is expressed specifically in neuronal and endocrine cells. SCG3 was synthesized as a 61- or 63-kDa protein and processed to a 48-kDa form which, in turn, was partially cleaved to fragments of 28 and 20 kDa.
|Product Specific Protocols|
|IHC protocol for Secretogranin III antibody 10954-1-AP||Download protocol|
|IF protocol for Secretogranin III antibody 10954-1-AP||Download protocol|
|Click here to view our Standard Protocols|
J Exp Med
Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.
The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells.
Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.
Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.
Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.
Adv Sci (Weinh)
Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation.