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- KD/KO Validated
Secretogranin III Polyclonal antibody
Secretogranin III Polyclonal Antibody for IF, IHC, ELISA
Cat no : 10954-1-AP
Validation Data Gallery
|Positive IHC detected in
|mouse pancreas tissue, human pancreas cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in
|mouse pancreas tissue
|IHC : 1:50-1:500
|IF : 1:50-1:500
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
10954-1-AP targets Secretogranin III in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
|human, mouse, rat
|Host / Isotype
|Rabbit / IgG
|Secretogranin III fusion protein Ag1397
|Calculated molecular weight
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Secretogranin III (SCG3), a member of the granin protein family, is expressed specifically in neuronal and endocrine cells. SCG3 was synthesized as a 61- or 63-kDa protein and processed to a 48-kDa form which, in turn, was partially cleaved to fragments of 28 and 20 kDa.
J Exp Med
Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy.
The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells.
Secretogranin III is an astrocyte granin that is overexpressed in reactive glia.
Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.
Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC.
Adv Sci (Weinh)
Tuning the Size of Large Dense-Core Vesicles and Quantal Neurotransmitter Release via Secretogranin II Liquid-Liquid Phase Separation.