Product Information
13080-1-PBS targets SLC25A32 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | SLC25A32 fusion protein Ag3722 Predict reactive species |
Full Name | solute carrier family 25, member 32 |
Calculated Molecular Weight | 315 aa, 35 kDa |
Observed Molecular Weight | 35-40 kDa |
GenBank Accession Number | BC021893 |
Gene Symbol | SLC25A32 |
Gene ID (NCBI) | 81034 |
RRID | AB_2877913 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9H2D1 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
Solute carrier family 25 member 32 (SLC25A32) can transfer tetrahydrofolate (THF) from cellular cytoplasm to the mitochondria as a mitochondrial folate transporter (MFT). It has been reported that SLC25A32 can also transport FAD across the mitochondrial inner membrane. Chronic alcohol exposure affects mitochondrial folate uptake and may affect the transcription of the SLC25A32. And functional SLC25A32 defect is associated with the cranial neural tube defects(PMID: 21956163; 29666258)