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SREBF2 Polyclonal antibody

SREBF2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human and More (3)

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 28212-1-AP

Synonyms

bHLHd2, SREBF2, SREBP 2, SREBP2



Tested Applications

Positive WB detected inHUVEC cells, HeLa cells, HepG2 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:8000
Sample-dependent, check data in validation data gallery

Product Information

28212-1-AP targets SREBF2 in WB, IHC, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman, mouse, hamster
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen SREBF2 fusion protein Ag28205
Full Name sterol regulatory element binding transcription factor 2
Calculated molecular weight 124 kDa
Observed molecular weight73-75 kDa, 120-130 kDa
GenBank accession numberBC056158
Gene symbol SREBF2
Gene ID (NCBI) 6721
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

SREBF2,also named as BHLHD2, is a 1141 amino acid protein, which contains 1 bHLH domain and belongs to the SREBP family. SREBF2 localizes in the endoplasmic reticulum membrane and is ubiquitously expressed in adult and fetal tissues. SREBF2 as a transcriptional activator is required for lipid homeostasis. SREBF2 expression is dynamically regulated in response to nutritional and hormonal cues. SREBF2 exists two isoform with molecular weight 124 kDa and 73 kDa.

Protocols

Product Specific Protocols
WB protocol for SREBF2 antibody 28212-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Mol Metab

CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.

Authors - Han Zeng
human,mouseWB

Cancer Commun (Lond)

PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.

Authors - Weixing Dai
humanWB

Front Cell Dev Biol

The Chromatin Remodeling Protein BRG1 Regulates SREBP Maturation by Activating SCAP Transcription in Hepatocytes.

Authors - Ming Kong
humanWB

Front Oncol

A Novel c-MET-Targeting Antibody-Drug Conjugate for Pancreatic Cancer.

Authors - Yangbing Jin
mouseWB

Biochim Biophys Acta Mol Basis Dis

The role of AMPKα2 in the HFD-induced nonalcoholic steatohepatitis.

Authors - Xuejiao Zhang
humanWB

Front Pharmacol

SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis.

Authors - Tingting Zhu