|Positive WB detected in||HUVEC cells, HeLa cells, HepG2 cells|
|Western Blot (WB)||WB : 1:1000-1:8000|
|Sample-dependent, check data in validation data gallery|
28212-1-AP targets SREBF2 in WB, IHC, ELISA applications and shows reactivity with Human samples.
|Cited Reactivity||human, mouse, hamster|
|Host / Isotype||Rabbit / IgG|
|Immunogen||SREBF2 fusion protein Ag28205|
|Full Name||sterol regulatory element binding transcription factor 2|
|Calculated molecular weight||124 kDa|
|Observed molecular weight||73-75 kDa, 120-130 kDa|
|GenBank accession number||BC056158|
|Gene ID (NCBI)||6721|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
SREBF2,also named as BHLHD2, is a 1141 amino acid protein, which contains 1 bHLH domain and belongs to the SREBP family. SREBF2 localizes in the endoplasmic reticulum membrane and is ubiquitously expressed in adult and fetal tissues. SREBF2 as a transcriptional activator is required for lipid homeostasis. SREBF2 expression is dynamically regulated in response to nutritional and hormonal cues. SREBF2 exists two isoform with molecular weight 124 kDa and 73 kDa.
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