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- KD/KO Validated
SREBF2 Polyclonal antibody
SREBF2 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human and More (3)
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
Cat no : 28212-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HUVEC cells, HeLa cells, HepG2 cells |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:1000-1:8000 |
Sample-dependent, check data in validation data gallery |
Published Applications
KD/KO | See 3 publications below |
WB | See 22 publications below |
IHC | See 1 publications below |
Product Information
28212-1-AP targets SREBF2 in WB, IHC, ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Cited Reactivity | human, mouse, hamster |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | SREBF2 fusion protein Ag28205 |
Full Name | sterol regulatory element binding transcription factor 2 |
Calculated molecular weight | 124 kDa |
Observed molecular weight | 73-75 kDa, 120-130 kDa |
GenBank accession number | BC056158 |
Gene symbol | SREBF2 |
Gene ID (NCBI) | 6721 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SREBF2,also named as BHLHD2, is a 1141 amino acid protein, which contains 1 bHLH domain and belongs to the SREBP family. SREBF2 localizes in the endoplasmic reticulum membrane and is ubiquitously expressed in adult and fetal tissues. SREBF2 as a transcriptional activator is required for lipid homeostasis. SREBF2 expression is dynamically regulated in response to nutritional and hormonal cues. SREBF2 exists two isoform with molecular weight 124 kDa and 73 kDa.
Protocols
Product Specific Protocols | |
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WB protocol for SREBF2 antibody 28212-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Mol Metab CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing. | ||
Cancer Commun (Lond) PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism. | ||
Front Cell Dev Biol The Chromatin Remodeling Protein BRG1 Regulates SREBP Maturation by Activating SCAP Transcription in Hepatocytes. | ||
Biochim Biophys Acta Mol Basis Dis The role of AMPKα2 in the HFD-induced nonalcoholic steatohepatitis. | ||
Front Pharmacol SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis. |