TEAD4 Polyclonal antibody

TEAD4 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, CoIP, ELISA

Conjugate

Unconjugated

Cat no : 12418-1-AP

Synonyms

EFTR 2, hRTEF 1B, RTEF1, TCF13L1, TEA domain family member 4, TEAD 4, TEAD4, TEF 3, TEF3, TEFR 1, Transcription factor 13 like 1, Transcription factor RTEF 1



Tested Applications

Positive WB detected inBGC-823 cells, MCF-7 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
Sample-dependent, check data in validation data gallery

Product Information

12418-1-AP targets TEAD4 in WB, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TEAD4 fusion protein Ag3059
Full Name TEA domain family member 4
Calculated molecular weight 434 aa, 48 kDa
Observed molecular weight 65 kDa
GenBank accession numberBC015497
Gene symbol TEAD4
Gene ID (NCBI) 7004
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TEAD4 belongs to a protein family that share the TEA/ATTS domain. The transcriptional activity of TEAD4 required several regions of the proteins , a TBP-associated factor and a limiting transcriptional intermediary facotrs. TEAD4 also preforms an essential role in the Hippo signaling pathway. TEAD4 regulates gene expression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction. The calculated molecular weight of TEAD4 is 48 kDa, but molecular weight of TEAD4 is detected about 65 kDa as same as the result from the paper (PMID: 28051067).

Protocols

Product Specific Protocols
WB protocol for TEAD4 antibody 12418-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanCoIP

J Cell Mol Med

PMID: 31559693

Authors - Yangyang Yao
humanWB

J Oral Pathol Med

Systematic screening identifies a TEAD4-S100A13 axis modulating cisplatin sensitivity of oral squamous cell carcinoma cells.

Authors - Ruicen Li
  • KD Validated
humanWB

Mol Carcinog

YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.

Authors - Ya Li
humanWB,CoIP

J Cell Mol Med

NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.

Authors - Bowen Hu
  • KD Validated
mouseWB

J Cell Biol

Thyroid hormone regulates muscle fiber type conversion via miR-133a1.

Authors - Duo Zhang