TIA1 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 12133-2-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 35 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells, mouse spleen tissue, mouse thymus tissue, Raji cells

Positive IP detected in:
Jurkat cells

Positive IHC detected in:
human lymphoma tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
TIA1 cytotoxic granule-associated RNA binding protein

Calculated molecular weight:
214aa,24 kDa,43 kDa

Observed molecular weight:
40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TIA1

Synonyms
Nucleolysin TIA 1 isoform p40, p40 TIA 1, RNA binding protein TIA 1, TIA 1, TIA1
Background

TIA1, also named as p40-TIA-1, is involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). It possesses nucleolytic activity against cytotoxic lymphocyte target cells. TIA1 may be involved in apoptosis. Two isoforms of this protein exist - 41kDa and 42kDa.


Back
to top