TRPV1 Monoclonal antibody

TRPV1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1


Human and More (2)







Cat no : 66983-1-Ig


Capsaicin receptor, DKFZp434K0220, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1

Tested Applications

Positive WB detected inHepG2 cells, MDA-MB-468 cells, T-47D cells, HEK-293 cells, Y79 cells, HUVEC cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

66983-1-Ig targets TRPV1 in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman, sheep
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen TRPV1 fusion protein Ag18683
Full Name transient receptor potential cation channel, subfamily V, member 1
Calculated Molecular Weight 839 aa, 95 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC132820
Gene Symbol TRPV1
Gene ID (NCBI) 7442
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TRPV1, also named as VR1 or OTRPC1, belongs to the transient receptor potential (TRP) family and TRPV subfamily (PMID: 17579562). TRPV1 is a ligand-activated non-selective calcium permeant cation channel expressed predominantly by sensory neurons (PMID: 10821274). It is involved in detection of noxious chemical and thermal stimuli. TRPV1 plays an important role in inflammatory thermal hyperalgesia (PMID: 10764638; 10821274).


Product Specific Protocols
WB protocol for TRPV1 antibody 66983-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Int J Mol Sci

The Contribution of TSLP Activation to Hyperalgesia in Dorsal Root Ganglia Neurons of a Rat.

Authors - Chun-Ching Lu

Biochim Biophys Acta Mol Basis Dis

Palmitic acid and trans-4-hydroxy-3-methoxycinnamate, the active ingredients of Yaobishu formula, reduce inflammation and pain by regulating gut microbiota and metabolic changes after lumbar disc herniation to activate autophagy and the Wnt/β-catenin pathway

Authors - ShuoQi Li


Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis

Authors - Zhongyang Lv

Int J Mol Sci

Luteolin Alleviates Oxidative Stress in Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke via Modulation of the TRPV1 and CYP2A13/NRF2 Signaling Pathways

Authors - Lina Zhou

J Inflamm Res

Cannabidiol Inhibits Inflammation Induced by Cutibacterium acnes-Derived Extracellular Vesicles via Activation of CB2 Receptor in Keratinocytes

Authors - Ziqi Jiang

Cell Calcium

Liquiritin, a novel inhibitor of TRPV1 and TRPA1, protects against LPS-induced acute lung injury.

Authors - Zhenhong Liu


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Shihab (Verified Customer) (09-17-2021)

This antibody was tried in a cell type (cannot disclose) which has previously been shown to express plenty of TRPV1 signal. However, this antibody was unable to give any signal in various attempts at staining, even at 1:100 dilution. This is not to say that this anybody is not good because I have had trouble with various TRPV1 antibodies in this tissue type but it will be used in other cell/tissue type to see its staining capabilities

  • Applications: Immunofluorescence
  • Primary Antibody Dilution: 1:100