UNC93B1 Polyclonal antibody, PBS Only

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  WB analysis using 28359-1-AP (same clone as 28359-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28359-1-AP (UNC93B1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28359-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 28359-1-AP (same clone as 28359-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 28359-1-AP (UNC93B1 antibody) at dilution of 1:100 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28359-1-PBS in a different storage buffer formulation.

UNC93B1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 28359-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat, pig

Applications

WB, IHC, Indirect ELISA

Synonyms

UNC93, Unc 93B1, unc 93 homolog B1 (C. elegans), Protein unc-93 homolog B1, Protein unc 93 homolog B1

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Product Information

28359-1-PBS targets UNC93B1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

• Tested Reactivity: human, mouse, rat, pig
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: UNC93B1 fusion protein Ag27937
• Full Name: unc-93 homolog B1 (C. elegans)
• Calculated Molecular Weight: 597 aa, 67 kDa
• Observed Molecular Weight: ~70 kDa
• GenBank Accession Number: BC101568
• Gene Symbol: UNC93B1
• Gene ID (NCBI): 81622
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H1C4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Unc-93 homolog B1 (UNC93B1) is a key regulator of nucleic acid (NA)-sensing Toll-like receptors (TLRs). UNC93B1 plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. It's a transmembrane protein that is known to control the movement of TLRs from the endoplasmic reticulum-where TLRs are assembled-to endosomes. The calculated MW of UNC93B1 is 66 kDa, 28359-1-AP can detect a band around 70 kDa.