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UQCRC1 Polyclonal antibody

UQCRC1 Polyclonal Antibody for WB, IP, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 21705-1-AP


Complex III subunit 1, Core protein I, D3S3191, QCR1, UQCR1, UQCRC1

Tested Applications

Positive WB detected inHeLa cells, human brain tissue, human skeletal muscle tissue, mouse skeletal muscle tissue, human heart tissue, mouse large intestine tissue, mouse kidney tissue, mouse spleen tissue, L02 cells, mouse liver tissue, rat liver tissue, Jurkat cells
Positive IP detected inHeLa cells
Positive IHC detected inhuman heart tissue, human liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:8000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

21705-1-AP targets UQCRC1 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen UQCRC1 fusion protein Ag16322
Full Name ubiquinol-cytochrome c reductase core protein I
Calculated Molecular Weight 480 aa, 53 kDa
Observed Molecular Weight 45 kDa
GenBank Accession NumberBC009586
Gene Symbol UQCRC1
Gene ID (NCBI) 7384
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

UQCRC1(Cytochrome b-c1 complex subunit 1, mitochondrial), also named as QCR1 and UQCR1, is a ubunit of the cytochrome bc1 complex (complex III) of the mitochondrial respiratory chain, may mediate the formation of the complex between cytochromes c and c1. The gene encodes a 53 kDa protein with a 34 amino acids transit peptide. It is associated with apoptosis or inhibition of cancer cell growth.


Product Specific Protocols
WB protocol for UQCRC1 antibody 21705-1-APDownload protocol
IHC protocol for UQCRC1 antibody 21705-1-APDownload protocol
IF protocol for UQCRC1 antibody 21705-1-APDownload protocol
IP protocol for UQCRC1 antibody 21705-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Sci Bull (Beijing)

Targeted clearance of mitochondria by an autophagy-tethering compound (ATTEC) and its potential therapeutic effects

Authors - Shuixia Tan


Role of molybdenum in material immunomodulation and periodontal wound healing: Targeting immunometabolism and mitochondrial function for macrophage modulation.

Authors - Xiao-Tao He


Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer.

Authors - Qing Wang

Acta Pharmacol Sin

MicroRNA-214 contributes to Ang II-induced cardiac hypertrophy by targeting SIRT3 to provoke mitochondrial malfunction.

Authors - Yan-Qing Ding

Int J Nanomedicine

Activation of Dynamin-Related Protein 1 and Induction of Mitochondrial Apoptosis by Exosome-Rifampicin Nanoparticles Exerts Anti-Osteosarcoma Effect

Authors - Wenkai Chen

Aging (Albany NY)

Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism.

Authors - Delong Yin


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Xingyuan (Verified Customer) (06-30-2023)

Quality was alright, had non-specific band under it.

  • Applications: Western Blot
  • Cell Tissue Type: 293T
UQCRC1 Antibody Western Blot validation ( dilution) in 293T (Cat no:21705-1-AP)

Xingyuan (Verified Customer) (06-30-2023)

Quality was alright, had non-specific band under it.

  • Applications: Western Blot
  • Cell Tissue Type: 293T