dysferlin Polyclonal antibody, PBS Only

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  WB analysis using 31658-1-AP (same clone as 31658-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31658-1-AP (dysferlin antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31658-1-PBS in a different storage buffer formulation.

dysferlin Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31658-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

31658-1-PBS targets dysferlin in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: dysferlin fusion protein Ag35810
• Full Name: dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
• Calculated Molecular Weight: 237 kDa
• Observed Molecular Weight: 240 kDa
• GenBank Accession Number: NM_001130455
• Gene Symbol: DYSF
• Gene ID (NCBI): 8291
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: O75923
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Dysferlin, also known as FER1L1, belongs to the ferlin family and is a member of a putative muscle-specific repair complex. It has many isoforms and is a large membrane protein that is most abundant in striated muscle. It plays a role in sarcolemmal repair and is a key calcium ion sensor involved in Ca(2+)-triggered synaptic vesicle-plasma membrane fusion.