ADAM28 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22234-1-AP

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Freight/Packing

Con: 51 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse lung tissue, BxPC-3 cells, mouse colon tissue, mouse liver tissue, mouse small intestine tissue, mouse spleen tissue, PC-13 cells

Positive IP detected in:
mouse lung tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ADAM metallopeptidase domain 28

Calculated molecular weight:
775aa,87 kDa

Observed molecular weight:
35 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADAM28

Synonyms
ADAM 28, ADAM28, eMDC II, eMDCII, MDC L, MDC Lm, MDC Ls, MDCL
Background

ADAM28 belongs to a family of cell surface and secreted glycoproteins that possess both proteolytic and adhesive properties. ADAM28 is predominantly expressed by carcinoma cells in the breast carcinoma tissues as protein bands of 42 kDa and 55/57 kDa, which correspond to the active forms of ADAM28s and ADAM28m, respectively.In human non-small cell lung carcinomas and breast carcinomas, ADAM28 is overexpressed predominantly by carcinoma cells, and the expression correlates with carcinoma cell proliferation and lymph node metastasis(PMID:19601836).


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