ADIPOQ Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21613-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
NIH/3T3 cells, 3T3-L1 cells

Positive IHC detected in:
human liver tissue,human skin tissue

Positive IF detected in:
NIH/3T3 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
adiponectin, C1Q and collagen domain containing

Calculated molecular weight:
244aa,26 kDa

Observed molecular weight:
29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADIPOQ

Synonyms
ACDC, ACRP30, adiponectin, ADIPOQ, ADIPQTL1, ADPN, APM 1, APM1, GBP28, Gelatin binding protein
Background

Adiponectin (AdipoQ), an adipocyte-derived hormone, is one of the most abundant adipokines in the blood circulation. Adiponectin modulates a number of metabolic processes, including improving insulin sensitivity and anti-inflammatory activity. The role of AdipoQ in reproduction is not yet fully understood, but the expression of AdipoQ in reproductive tissues has been observed in various animals and humans, including chicken testis, bovine ovary, and human placenta. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2. AdipoR1 is expressed primarily in the skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. AdipoQ May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors.


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