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  • KD/KO Validated

Adiponectin receptor Antibody

Adiponectin receptor Polyclonal Antibody for IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IP, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 14361-1-AP

Synonyms

ACDCR2, adiponectin receptor 2, Adiponectin receptor protein 2, ADIPOR1, ADIPOR2, PAQR2



Tested Applications

Positive WB detected inL02 cells, HeLa cells, mouse uterus tissue
Positive IP detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Sample-dependent, check data in validation data gallery

Product Information

14361-1-AP targets Adiponectin receptor in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity hamster, human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Adiponectin receptor fusion protein Ag5744
Full Name adiponectin receptor 2
Calculated molecular weight 44 kDa
Observed molecular weight 44-50 kDa
GenBank accession numberBC051858
Gene symbol ADIPOR2
Gene ID (NCBI) 79602
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa. This antibody raised against 1-147aa of human AdipoR2 may cross-react with AdipoR1.

Protocols

Product Specific Protocols
WB protocol for Adiponectin receptor antibody 14361-1-APDownload protocol
IP protocol for Adiponectin receptor antibody 14361-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IHC

Int J Biol Sci

Adiponectin Suppresses Human Pancreatic Cancer Growth through Attenuating the β-Catenin Signaling Pathway.

Authors - Jinghui Jiang
  • KD Validated
mouseWB

Oncotarget

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice.

Authors - Jian Hong
ratWB, IHC

Ann Hepatol

Effects of a low-fat diet on the hepatic expression of adiponectin and its receptors in rats with NAFLD.

Authors - Hong Ma
mouseWB

PLoS One

PMID: 30308063

Authors - Rika Ito
mouseWB

Nutrition

Fenugreek galactomannan and citrus pectin improve several parameters associated with glucose metabolism and modulate gut microbiota in mice.

Authors - Miriam G Shtriker
hamsterWB

Cancer Sci

Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.

Authors - Haoyi Jin