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Adiponectin receptor Polyclonal antibody

Adiponectin receptor Polyclonal Antibody for IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (2)

Applications

WB, IP, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 14361-1-AP

Synonyms

ACDCR2, adiponectin receptor 2, Adiponectin receptor protein 2, ADIPOR1, ADIPOR2, PAQR2



Tested Applications

Positive WB detected inHeLa cells, A549 cells, human placenta tissue, rat liver tissue, L02 cells
Positive IP detected inmouse liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14361-1-AP targets Adiponectin receptor in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, hamster, pig
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Adiponectin receptor fusion protein Ag5744
Full Name adiponectin receptor 2
Calculated Molecular Weight 44 kDa
Observed Molecular Weight 40-45 kDa
GenBank Accession NumberBC051858
Gene Symbol ADIPOR2
Gene ID (NCBI) 79602
RRIDAB_2222052
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa. This antibody raised against 1-147aa of human AdipoR2 may cross-react with AdipoR1.

Protocols

Product Specific Protocols
WB protocol for Adiponectin receptor antibody 14361-1-APDownload protocol
IP protocol for Adiponectin receptor antibody 14361-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIF

Redox Biol

Melatonin improves cardiac function in a mouse model of heart failure with preserved ejection fraction.

Authors - Yuan Liu
hamsterWB

Cancer Sci

Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.

Authors - Haoyi Jin
mouseWB

Food Funct

Quercetin regulates skeletal muscle fiber type switching via adiponectin signaling.

Authors - Xiaoling Chen
mouseWB

Food Funct

D-chiro-Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition.

Authors - Qiong Yang
ratWB,IF

J Alzheimers Dis

Advanced Glycosylation End Products Induced Synaptic Deficits and Cognitive Decline Through ROS-JNK-p53/miR-34c/SYT1 Axis in Diabetic Encephalopathy

Authors - Rui Zhang
mouseWB

Gene

The Mef2c/AdipoR1 axis is responsible for myogenic differentiation and is regulated by resistin in skeletal muscles

Authors - Fengyun Wen