AIFM2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20886-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human

Positive IP detected in:
L02 cells

Positive IHC detected in:
human liver tissue

Recommended dilution:
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
apoptosis-inducing factor, mitochondrion-associated, 2

Calculated molecular weight:
41 kDa

Observed molecular weight:
41 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AIFM2

Synonyms
AIFM2, AMID, Apoptosis inducing factor 2, p53 responsive gene 3 protein, PRG3, RP11 367H5.2
Background

The human AIFM2 protein (formerly known as AMID) is an apoptosis associated flavoprotein with a 6-hydroxy FAD cofactor. AIFM2 is a NAD(P)H-binding oxidoreductase with some sequence similarities to A1FM1 (formerly known as AIF, Apoptosis Inducing Factor), a mitochondrion-associated enzyme which relocates to the cell nucleus during apoptosis and is considered to be a key player in the progression of cell death.


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