ARNT,HIF1B Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 14105-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 45 μg/150 μl

Choose size:

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Species specificity:
human, mouse

Positive WB detected in:
HepG2 cells,HeLa cells

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
mouse embryo tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
aryl hydrocarbon receptor nuclear translocator

Calculated molecular weight:
416aa,46 kDa,87 kDa

Observed molecular weight:
86 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARNT

Synonyms
ARNT, ARNT protein, bHLHe2, HIF 1 beta, HIF 1beta, HIF1 beta, HIF1B, HIF1BETA, TANGO
Background

HIF1B, also named as ARNT, is a 789 amino acid protein, which forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. HIF1B is Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia


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