BAD Antibody 12 Publications

Rabbit Polyclonal| Catalog number: 10435-1-AP

Featured Product KD/KO validated

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Con: 31 μg/150 μl

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Species specificity:
human, mouse, rat, sheep

Positive WB detected in:
mouse heart tissue, Tunicamycin treated HeLa cells, HeLa cells

Positive IHC detected in:
human prostate hyperplasia tissue, human lymphoma tissue, human prostate hyperplasia tissue

Recommended dilution:
WB : 1:300-1:1000
IHC : 1:100-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
BCL2-associated agonist of cell death

Calculated molecular weight:
18 kDa

Observed molecular weight:
15-18 kDa; 25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BAD

Synonyms
BAD, BBC2, BBC6
Background

BAD, also named as BBC6 and BCL2L8, promotes cell death. It is successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. It appears to act as a link between growth factor receptor signaling and the apoptotic pathways.


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