C5aR Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 21316-1-AP

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Freight/Packing

Con: 32 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
PC-3 cells, L02 cells, mouse kidney tissue, mouse liver tissue, rat liver tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human liver tissue, human liver tissue, human lung tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
PC-3 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
complement component 5a receptor 1

Calculated molecular weight:
350aa,39 kDa

Observed molecular weight:
45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
C5AR1

Synonyms
C5A, C5a R, C5aR, C5AR1, C5R1, CD88
Background

C5aR, also named as CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.


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