Cyclin E1 Antibody 32 Publications

Rabbit Polyclonal| Catalog number: 11554-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 47 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, Artemia, zebrafish

Positive WB detected in:
MCF-7 cells, HeLa cells, human lung tissue, Jurkat cells, K-562 cells, mouse heart tissue, NIH/3T3 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cyclin E1

Calculated molecular weight:
410aa,47 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CCNE1

Synonyms
CCNE, CCNE1, cyclin E1, G1/S specific cyclin E1
Background

Cyclin E1 (CCNE1) is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNE1, an essential cyclin activating Cdk2, regulates the G1-S phase transition of the mammalian cell division cycle. Its timing expression plays a direct role in the initiation of DNA replication , the control of histone biosynthesis, and the centrosome cycle. CCNE1 is associated with disease progression in various malignancies and is associated clinically with poor prognosis.


Back
to top