CDK4 Antibody 34 Publications

Rabbit Polyclonal| Catalog number: 11026-1-AP

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 53 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
HeLa cells, HeLa cells, HepG2 cells, rat pancreas tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human lung cancer tissue, human breast cancer tissue, human lung cancer tissue, human lymphoma tissue

Positive IF detected in:
MCF-7 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cyclin-dependent kinase 4

Calculated molecular weight:
34 kDa

Observed molecular weight:
34 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CDK4

Synonyms
CDK4, Cell division protein kinase 4, CMM3, cyclin dependent kinase 4, PSK J3
Background

Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1- to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level(PMID:17253961). CCND1-CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth(PMID:21844184).


Back
to top