CEACAM3-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19496-1-AP

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Freight/Packing

Con: 24 μg/150 μl

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Species specificity:
human

Positive IHC detected in:
human colon cancer tissue, human colon cancer tissue, human stomach cancer tissue

Positive FC detected in:
A431 cells

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
carcinoembryonic antigen-related cell adhesion molecule 3

Calculated molecular weight:
27 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CEACAM3

Synonyms
Carcinoembryonic antigen CGM1, CD66D, CEACAM3, CGM1, W264, W282
Background

CEACAM3, also named as CD66D and CGM1, belongs to the immunoglobulin superfamily and CEA family. CEACAM3 is the major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species. CEACAM3 plays an important role in the clearance of pathogens by the innate immune system. It is responsible for RAC1 stimulation in the course of pathogen phagocytosis. The antibody is specific to isoform1 of CEACAM3.


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