CEACAM3-Specific Polyclonal antibody

CEACAM3-Specific Polyclonal Antibody for FC, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, FC, ELISA

Conjugate

Unconjugated

Cat no : 19496-1-AP

Synonyms

Carcinoembryonic antigen CGM1, CD66D, CEACAM3, CGM1, W264, W282



Tested Applications

Positive IHC detected inhuman colon cancer tissue, human stomach cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive FC detected inA431 cells

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

19496-1-AP targets CEACAM3-Specific in IHC, FC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name carcinoembryonic antigen-related cell adhesion molecule 3
Calculated molecular weight 27 kDa
GenBank accession numberNM_001815
Gene symbol CEACAM3
Gene ID (NCBI) 1084
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CEACAM3, also named as CD66D and CGM1, belongs to the immunoglobulin superfamily and CEA family. CEACAM3 is the major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species. CEACAM3 plays an important role in the clearance of pathogens by the innate immune system. It is responsible for RAC1 stimulation in the course of pathogen phagocytosis. The antibody is specific to isoform1 of CEACAM3.

Protocols

Product Specific Protocols
IHC protocol for CEACAM3-Specific antibody 19496-1-APDownload protocol
FC protocol for CEACAM3-Specific antibody 19496-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols