CEP152 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21815-1-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue

Positive IP detected in:
mouse brain tissue

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
centrosomal protein 152kDa

Calculated molecular weight:
189 kDa

Observed molecular weight:
110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CEP152

Synonyms
centrosomal protein 152kDa, Centrosomal protein of 152 kDa, CEP152, KIAA0912
Background

CEP152, also named as KIAA0912, is a regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. It is necessary for centrosome duplication. CEP152 functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation. CEP152, ATR and CENPJ control cellular responses to DNA damage. CEP152 has some isoforms woth MW 189 kDa, 152 kDa, 110 kDa and 66 kDa.


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