CPT1A Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66039-1-Ig |CloneNo.: 5D8G9

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Con: 238 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
lo2 cells, L02 cells

Positive IP detected in:
MCF-7 cells

Positive IHC detected in:
human heart tissue, human heart tissue, human liver tissue

Positive FC detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
carnitine palmitoyltransferase 1A (liver)

Calculated molecular weight:
88 kDa

Observed molecular weight:
86 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CPT1A

Synonyms
CPT I, CPT1, CPT1 L, CPT1A, CPTI L, L CPT1
Background

CPT1A, also named as CPT1, CPT1-L and L-CPTI, belongs to the carnitine/choline acetyltransferase family. It is Localized Chromosome 11q13.1-2. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1A is an active forms of related liver-type carnitine palmitoyltransferase I. (PMID: 11001805). CPT1A deficiency presents as recurrent attacks of fasting hypoketotic hypoglycemia. (PMID: 15363638). This antibody can bind the close sequences genes.


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