CTP synthase Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 15914-1-AP

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Freight/Packing

Con: 24 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human liver cancer tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2400
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CTP synthase

Calculated molecular weight:
591aa,67 kDa

Observed molecular weight:
67 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CTPS

Synonyms
CTP synthase, CTP synthase 1, CTP synthetase 1, CTPS, UTP ammonia ligase 1
Background

CTP synthase(CTPS) is also named as CTPS1 and belongs to the CTP synthase family. It catalyses the ATP-dependent formation of CTP from UTP using either L-glutamine or NH3 as the nitrogen source(PMID:12752439). It is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis(PMID:8813694). CTP synthetase exists as a dimer in the absence of its substrates ATP and UTP, but in the presence of saturating concentrations of these substrates the enzyme exists as a tetramer.(PMID:18439916)


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