DDB1 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66010-1-Ig |CloneNo.: 4F6C6

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 65 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
Hela cells, A549 cells, HeLa cells, MCF-7 cells, NIH/3T3 cells, RAW 264.7 cells

Positive IHC detected in:
human cervical cancer tissue, human cervical cancer tissue, human testis tissue

Positive IF detected in:
Hela cells, MCF-7 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
damage-specific DNA binding protein 1, 127kDa

Calculated molecular weight:
1140aa,127 kDa

Observed molecular weight:
127 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DDB1

Synonyms
DDB p127 subunit, DDB1, DDBA, DNA damage binding protein 1, DNA damage binding protein a, HBV X associated protein 1, UV damaged DNA binding factor, UV DDB 1, UV DDB1, XAP 1, XAP1, XPCE, XPE, XPE BF, XPE binding factor
Background

DDB1, also named as XAP1, XPCe, DDBa and XPE-BF, belongs to the DDB1 family. It is required for DNA repair. DDB1 binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1. This antibody is specific to DDB1.


Back
to top