- Featured Product
- KD/KO Validated
CoraLite® Plus 488-conjugated DDB1 Monoclonal antibody
DDB1 Monoclonal Antibody for WB
Host / Isotype
Mouse / IgG2b
human, mouse, rat
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-66010
|Positive WB detected in
|Jurkat cells, HEK-293 cells, HeLa cells
|Western Blot (WB)
|WB : 1:500-1:2000
|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
CL488-66010 targets DDB1 in WB applications and shows reactivity with human, mouse, rat samples.
|human, mouse, rat
|Host / Isotype
|Mouse / IgG2b
|DDB1 fusion protein Ag17903
|damage-specific DNA binding protein 1, 127kDa
|Calculated molecular weight
|1140 aa, 127 kDa
|Observed molecular weight
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 488 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|493 nm / 522 nm
|Protein A purification
|PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
|Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
DDB1, also named as XAP1, XPCe, DDBa and XPE-BF, belongs to the DDB1 family. It is required for DNA repair. DDB1 binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1. This antibody is specific to DDB1.