|Positive WB detected in||U-251 cells|
|Western Blot (WB)||WB : 1:300-1:1200|
|Sample-dependent, check data in validation data gallery|
10592-1-AP targets DLX5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
|Reactivity||human, mouse, rat|
|Cited Species||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||DLX5 fusion protein Ag0910|
|Full Name||distal-less homeobox 5|
|Calculated molecular weight||32 kDa|
|Observed molecular weight||35 kDa|
|GenBank accession number||BC006226|
|Gene ID (NCBI)||1749|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.1% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20oC. Aliquoting is unnecessary for -20oC storage.|
DLX5 belongs to the DLX family of homeobox transcription factors (Dlx1, Dlx2, Dlx5 and Dlx6), which is expressed in overlapping domains at different stages of cell differentiation in the subpallium and controls differentiation of GABAergic neurons. DLX5 is an immediate early BMP-responsive transcriptional activator that essential for osteoblast differentiation. It can bind to and stimulate the homeodomain-response element of the ALPL and SP7 promoter. DLX5 can form homodimer with DLX2(~34kd) and heterodimer with MSX2(~29kd).
Involvement of microRNAs in regulation of osteoblastic differentiation in mouse induced pluripotent stem cells.
Arthritis Res Ther
Ossification process involving the human thoracic ligamentum flavum: role of transcription factors.