ERBB4 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 19943-1-AP

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Freight/Packing

Con: 25 μg/150 μl

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Species specificity:
human, mouse, rat, pig

Positive WB detected in:
mouse brain tissue, MCF-7 cells

Positive IHC detected in:
human kidney tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Calculated molecular weight:
147 kDa

Observed molecular weight:
147 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ERBB4

Synonyms
4ICD, E4ICD, ERBB4, HER4, p180erbB4, s80HER4
Background

ERBB4, also named as p180erbB4 and HER4, belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. ERBB4 specifically binds and it is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. Interaction with these factors induces cell differentiation. ERBB4 is not activated by EGF, TGF-A, and amphiregulin. ERBB4 catalyze the reaction: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. The antibody recognize the C-term of ERBB4.


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