Showing 1-  of  Publications
EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis.
By Product Type
By Research Area
Images See all
ERBB4, also named as p180erbB4 and HER4, belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. ERBB4 specifically binds and it is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. Interaction with these factors induces cell differentiation. ERBB4 is not activated by EGF, TGF-A, and amphiregulin. ERBB4 catalyze the reaction: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. The antibody recognize the C-term of ERBB4.