|Positive WB detected in||human plasma tissue|
|Positive IP detected in||human plasma tissue|
|Positive IF detected in||HUVEC cells|
|Western Blot (WB)||WB : 1:5000-1:50000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:5000-1:50000 for WB|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
The immunogen of 24295-1-AP is F2 Fusion Protein expressed in E. coli.
|Cited Reactivity||human, Plasmodium falciparum|
|Host / Isotype||Rabbit / IgG|
|Immunogen||F2 fusion protein Ag18385|
|Full Name||coagulation factor II (thrombin)|
|Calculated molecular weight||622 aa, 70 kDa|
|Observed molecular weight||72 kDa|
|GenBank accession number||BC051332|
|Gene ID (NCBI)||2147|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.1% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Factor II, or prothrombin, is one of the components of this chain of plasma proteins involved in blood coagulation. Thrombin is essential in the processes of hemostasis and thrombosis.
The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.