F8 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21485-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human

Positive WB detected in:
mouse liver tissue

Positive IF detected in:
human umbilical vein endothelial cells, HUVEC cells

Recommended dilution:
WB : 1:200-1:1000
IF : N/A

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
coagulation factor VIII, procoagulant component

Calculated molecular weight:
2351aa,267 kDa

Observed molecular weight:
25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
F8

Synonyms
AHF, Antihemophilic factor, Coagulation factor VIII, DXS1253E, F8, F8B, F8C, FVIII, HEMA, Procoagulant component
Background

F8, also named as AHF and F8C, belongs to the multicopper oxidase family. F8, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. F8 can be cleaved to 4 chains F8a heavy chain, 200 kd isoform, F8a heavy chain, 92 kd isoform, F8 B chain and F8a light chain. This antibody can recognize the light chain.


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