Fibrinogen gamma chain Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66158-1-Ig |CloneNo.: 2B2B8

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Con: 180 μg/150 μl

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Species specificity:
human

Positive WB detected in:
L02 cells

Positive IHC detected in:
human liver tissue, human kidney tissue, human liver tissue

Positive IF detected in:
L02 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Thiophilic Affinity Chromatography

Isotype:
IgM

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
fibrinogen gamma chain

Calculated molecular weight:
453aa,52 kDa;437aa,50 kDa

Observed molecular weight:
52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FGG

Synonyms
FGG, fibrinogen gamma chain
Background

Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGG is the gamma chain of fibrinogen. Mutations in the gene of FGG lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.


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