|Positive WB detected in||human plasma tissue|
|Positive IP detected in||human plasma tissue|
|Positive IF detected in||HUVEC cells|
|Western Blot (WB)||WB : 1:5000-1:50000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:5000-1:50000 for WB|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
24295-1-AP targets F2 in WB, IP, IF, ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, Plasmodium falciparum|
|Host / Isotype||Rabbit / IgG|
|Immunogen||F2 fusion protein Ag18385|
|Full Name||coagulation factor II (prothrombin)|
|Calculated molecular weight||622 aa, 70 kDa|
|Observed molecular weight||72 kDa|
|GenBank accession number||BC051332|
|Gene ID (NCBI)||2147|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Factor II, or prothrombin, is one of the components of this chain of plasma proteins involved in blood coagulation. Thrombin is essential in the processes of hemostasis and thrombosis.
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Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.
Thrombin cleavage of the hepatitis E virus polyprotein at multiple conserved locations is required for genome replication
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Elke (Verified Customer) (02-23-2023)
it can work on the western blot