GADD45A Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 13747-1-AP

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
PC-13 cells, A549 cells, COLO 320 cells, K-562 cells, mouse lung tissue, mouse spleen tissue, PC-13 cells, rat lung tissue

Positive IP detected in:
K-562 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
growth arrest and DNA-damage-inducible, alpha

Calculated molecular weight:
165aa,18 kDa

Observed molecular weight:
18 kDa or 36 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GADD45A

Synonyms
DDIT 1, DDIT1, GADD45, GADD45A
Background

GADD45A, also named as DDIT1 and GADD45, belongs to the GADD45 family. It binds to proliferating cell nuclear antigen. GADD45A may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. GADD45A has Dimer (~36 kDa) and Mono (~18 kDa) forms (PMID:11498536).


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