Name: GADD45A Rabbit Polyclonal antibody
Brand: Proteintech
SKU: 13747-1-AP

Tested Applications

Applications:

WB, IHC, ELISA
Application not tested? Please see our Guarantee

Species specificity:

human, mouse, rat

Recommended dilution:

Sample-dependent, check data in Validation tab

Product Information

Source:

Rabbit

Purification method:

Antigen affinity purification

Isotype:

IgG

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20^oC. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

Immunogen:

GADD45A fusion protein Ag4687

Full name:

growth arrest and DNA-damage-inducible, alpha

Calculated molecular weight:

165aa,18 kDa

Observed molecular weight:

GenBank accession number:

BC011757

Gene ID (NCBI):

1647

Gene symbol

GADD45A

Synonyms

DDIT 1, DDIT1, GADD45, GADD45A

Background

GADD45A, also named as DDIT1 and GADD45, belongs to the GADD45 family. It binds to proliferating cell nuclear antigen. GADD45A may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. GADD45A has Dimer (~36 kDa) and Mono (~18 kDa) forms (PMID:11498536).

Showing 1- [6] of [7] Publications

Author:		Gangjun Yuan
Pubmed ID:		29415747
Journal:		J Exp Clin Cancer Res
Title:		Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Application:		WB,IHC
KD validated
Species:		human

Author:		Jia Liu
Pubmed ID:		29515153
Journal:		Sci Rep
Title:		Down-regulation of GADD45A enhances chemosensitivity in melanoma.
Application:		WB

Species:		human

Author:		Pengli Zheng
Pubmed ID:		30030520
Journal:		Cell Res
Title:		DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Application:		WB

Species:		human

Author:		Bin Zhang
Pubmed ID:		31075266
Journal:		Biochem Pharmacol
Title:		Selective activation of tumor-suppressive MAPKP signaling pathway by triptonide effectively inhibits pancreatic cancer cell tumorigenicity and tumor growth.
Application:		WB

Species:		human

Author:		Yanjie Wang
Pubmed ID:		30640591
Journal:		Bosn J Basic Med Sci
Title:		CircRNA_014511 affects the radiosensitivity of bone marrow mesenchymal stem cells by binding to miR-29b-2-5p.
Application:		WB

Species:		mouse

Author:		Ji Zhou
Pubmed ID:		24981246
Journal:		Tumour Biol
Title:		Overexpression of HP1γ is associated with poor prognosis in non-small cell lung cancer cell through promoting cell survival.
Application:		WB

Species:		human

WB Figures

GADD45A Antibody WB A549 cells 13747-1-AP

A549 cells were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

GADD45A Antibody WB COLO 320 cells 13747-1-AP

COLO 320 cells were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

GADD45A Antibody WB K-562 cells 13747-1-AP

K-562 cells were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours

GADD45A Antibody WB mouse lung tissue 13747-1-AP

mouse lung tissue were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

GADD45A Antibody WB mouse spleen tissue 13747-1-AP

mouse spleen tissue were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

GADD45A Antibody WB PC-13 cells 13747-1-AP

PC-13 cells were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours

GADD45A Antibody WB rat lung tissue 13747-1-AP

rat lung tissue were subjected to SDS PAGE followed by western blot with 13747-1-AP( GADD45A Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

GADD45A Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 13747-1-AP

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Tested Applications

Product Information

Immunogen Information

Background

Showing 1- [6] of [7] Publications

WB Figures

Product-specific protocols

Standard Protocols

GADD45A Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 13747-1-AP

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Tested Applications

Product Information

Immunogen Information

Background