GLUD1 Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 14299-1-AP

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Freight/Packing

Con: 21 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HepG2 cells, mouse liver tissue, mouse lung tissue, PC-3 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human gliomas tissue

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glutamate dehydrogenase 1

Calculated molecular weight:
61 kDa

Observed molecular weight:
45-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GLUD1

Synonyms
GDH, GDH 1, GDH1, GLUD, GLUD1, glutamate dehydrogenase 1
Background

Human glutamate dehydrogenase (GDH), an enzyme central to the metabolism of glutamate, is known to exist in housekeeping and nerve tissue-specific isoforms encoded by the GLUD1 and GLUD2 genes, respectively. It catalyses the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, thus interconnecting amino acid and carbohydrate metabolism. GLUD1 might contribute to the formation of specific synapses in the hippocampus such as those formed by the projecting neurons of the entorhinal cortex(PMID: 22138648). GLUD1 has a calculated molecular mass of 61 kDa and an apparent molecular mass of 45-55 kDa with the 53aa transit peptide removed.


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