GPI Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 15171-1-AP

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Freight/Packing

Con: 33 μg/150 μl

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Species specificity:
human, mouse, rat, pig

Positive WB detected in:
PC-3 cells, HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
PC-3 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:100-1:400
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
glucose phosphate isomerase

Calculated molecular weight:
63 kDa

Observed molecular weight:
63 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GPI

Synonyms
AMF, Autocrine motility factor, g6pi, Glucose 6 phosphate isomerase, glucose phosphate isomerase, GNPI, GPI, Neuroleukin, NLK, PGI, PHI, Phosphoglucose isomerase, Phosphohexose isomerase, SA 36, Sperm antigen 36
Background

GPI(Glucose-6-phosphate isomerase),which is also named as autocrine motility factor (AMF), phosphoglucose isomerase(PGI), Neuroleukinis(NLK), phosphohexose isomerase(PHI), sperm antigen 36(SA-36), is a housekeeping cytosolic enzyme that plays a key role in both glycolysis and gluconeogenesis pathways. It is also a multifunctional protein that displays cytokine properties, eliciting mitogenic, motogenic, and differentiation activities, and has been implicated in tumor progression and metastasis(PMID:12783864). This protein can exsit as a homodimer in the catalytically active form and a monomer in the secreted form(PMID:11371164). It has 2 isoforms produced by alternative splicing.


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