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HYDIN (hydrocephalus inducing homolog), also named as HYDIN1 or HYDIN2, is a 5121 amino acid protein, which localizes in the cell projection HYDIN exists as seven alternatively spliced isoforms and is expressed in the ciliated ependymal cell layer of heart ventricle. HYDIN is also found in ciliated epithelial cells of developing spermatocytes, oviduct and bronchi and is required for ciliary motility. HYDIN gene mutation is involved in Ciliary dyskinesia primary 5.