ID1 Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 18475-1-AP

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Freight/Packing

Con: 61 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
PC-3 cells

Positive IF detected in:
PC-3 cells

Recommended dilution:
WB : 1:500-1:1000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

Calculated molecular weight:
16 kDa

Observed molecular weight:
20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ID1

Synonyms
bHLHb24, ID, ID1, Inhibitor of DNA binding 1
Background

ID (inhibitor of DNA binding) proteins contain a helix-loop-helix (HLH) motif and regulate tissue-specific transcription within several cell lineages. They do not bind DNA directly, but inhibit lineage commitment by binding basic helix-loop-helix (bHLH) transcription factors through their HLH motif. ID1 proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID proteins contribute to cell growth, senescence, differentiation, and angiogenesis.


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