IFT88 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60227-1-Ig |CloneNo.: 4A4G5

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Con: 137 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Human testis, human testis tissue

Positive IP detected in:
PC-3 cells

Positive IHC detected in:
human kidney tissue, human heart tissue, human kidney tissue, human pancreas tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
intraflagellar transport 88 homolog (Chlamydomonas)

Calculated molecular weight:
94 kDa

Observed molecular weight:
88-95 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IFT88

Synonyms
IFT88, TPR repeat protein 10, TTC10
Background

Intraflagellar transport (IFT), mediated by molecular motors and IFT particles, is an important transport process that occurs in the cilium and has been shown to be essential for the assembly and maintenance of cilia and flagella in many organisms. IFT88 (intraflagellar transport protein 88; also known as TG737 or TTC10) is a component of IFT particles and required for cilium biogenesis. Defects in IFT88/Tg737 lead to polycystic kidney disease (11062270). IFT88 localizes to spindle poles during mitosis and is required for spindle orientation in mitosis (21441926). This antibody was raised against the C-terminal region of human IFT88 and can detect the endogenous level of IFT88.


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