IL1 beta Antibody 6 Publications

Mouse Monoclonal| Catalog number: 60136-1-Ig |CloneNo.: 1C6F12

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Freight/Packing

Con: 75 μg/150 μl

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Species specificity:
human, mouse, rat

Recommended dilution:

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 1, beta

Calculated molecular weight:
269aa,31 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL1B

Synonyms
Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL-1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta
Background

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15 to 18 kDa protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets. The expression level of IL-1B is very low.


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