IMPDH2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55398-1-AP

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Con: 95 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A549 cells, K-562 cells, mouse skeletal muscle tissue

Positive IHC detected in:
human brain

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
IMP (inosine monophosphate) dehydrogenase 2

Calculated molecular weight:
56 kDa

Observed molecular weight:
56kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IMPDH2

Synonyms
IMPDH2, IMPDH II, IMPDH 2, IMPD2, IMPD 2
Background

IMPDH2, also named as IMPD2, belongs to the IMPDH/GMPR family. It is a rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. IMPDH2 is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. (PMID:21181270)This antibody is specific to IMPDH2.


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