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Integrin beta-1 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 12594-1-AP

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Con: 97 μg/150 μl

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Tested Applications
Applications:
ELISA, IHC, WB
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Images See all

12594-1-AP;HT-1080 cells

HT-1080 cells were subjected to SDS PAGE followed by western blot with 12594-1-AP (Integrin beta-1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours

12594-1-AP;human placenta tissue

Immunohistochemistry of paraffin-embedded human placenta tissue slide using 12594-1-AP( Integrin beta-1 Antibody) at dilution of 1:200 (under 40x lens).

Species specificity:
human, mouse, rat
Positive WB detected in:
HT-1080 cells, HeLa cells
Positive IHC detected in:
human placenta tissue, human breast cancer tissue, mouse kidney tissue
Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Integrin beta-1 fusion protein Ag3078
Full name:
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
Calculated molecular weight:
130 kDa
Observed molecular weight:
130 kDa
GenBank accession number:
BC020057
Gene ID (NCBI):
3688
Gene symbol
ITGB1
Synonyms
CD29, FNRB, GPIIA, Integrin beta 1, ITB1, ITGB1, MDF2, MSK12, VLA 4 subunit beta, VLA BETA, VLAB
Background

Integrin beta-1 (ITGB1), also named as CD29, is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.


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