Melanophilin Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66092-1-Ig |CloneNo.: 1A8D12

  • Print page
  • Download PDF

Be the first to review this product



Con: 115 μg/150 μl

Choose size:

Please visit your regions distributor:

Species specificity:
human, pig

Positive WB detected in:
HEK-293 cells, pig brain tissue, PC-3 cells

Positive IHC detected in:
human skin cancer tissue, human kidney tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:6000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Purification method:
Protein G purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:

Calculated molecular weight:
66 kDa

Observed molecular weight:
66 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

Exophilin 3, melanophilin, MLPH, SLAC2 A, SLAC2A, Synaptotagmin like protein 2a

Melanophilin (MLPH) is a member of the exophilin subfamily of Rab effector proteins. MLPH is a modular protein, forming a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. It regulates retention of melanosomes at the peripheral actin cytoskeleton of melanocytes, a process essential for normal mammalian pigmentation. Defects in MLPH are a cause of Griscelli syndrome type 3 (GS3), which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft.

to top