MYOD1 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66214-1-Ig |CloneNo.: 5D1D12

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Freight/Packing

Con: 220 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
human skeletal muscle tissue

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
myogenic differentiation 1

Calculated molecular weight:
320aa,35 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MYOD1

Synonyms
bHLHc1, Myf 3, MYF3, MYOD, MYOD1, myogenic differentiation 1, Myogenic factor 3, PUM
Background

MYOD1, also named as BHLHC1 or MYF3, is a 320 amino acid protein, which promotes the transcriptional activity of MYOD1 through its CDK9-mediated phosphorylation. This phosphorylation promotes its function in muscle differentiation. MYOD1 acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. MYOD1 together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. he calcualted molecular weight of MYOD1 is 34 kDa, but modified MYOD1 is about 45-47 kDa. (PMID: 12037670)


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