NAPRT1 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66159-1-Ig |CloneNo.: 5D8H10

Featured Product KD/KO validated

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Freight/Packing

Con: 220 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HeLa cells, HepG2 cells

Positive IHC detected in:
human small intestine tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
nicotinate phosphoribosyltransferase domain containing 1

Calculated molecular weight:
514aa,55 kDa

Observed molecular weight:
51 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NAPRT1

Synonyms
FHA HIT interacting protein, FHIP, NAPRT1, NAPRTase, PP3856
Background

Nicotinic acid (NA) is a coenzyme in cellular redox reactions, and is an essential component of metabolic pathways in all living cells. NAPRT1 (Nicotinate phosphoribosyltransferase) is essential for increasing cellular NAD levels and, thus, to prevent oxidative stress of cells. NAPRT1 converts Nicotinic acid (NA; niacin) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD).


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