Napsin A Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 16558-1-AP

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Con: 30 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse liver tissue

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
PC-3 cells

Recommended dilution:
WB : 1:200-1:600
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
napsin A aspartic peptidase

Calculated molecular weight:
420aa,45 kDa

Observed molecular weight:
45-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NAPSA

Synonyms
Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02
Background

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).


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