Neuropeptide Y Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 12833-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse

Positive IHC detected in:
human brain tissue, human brain tissue, human pancreas cancer tissue, mouse brain tissue

Positive IF detected in:
mouse brain tissue

Recommended dilution:
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
neuropeptide Y

Calculated molecular weight:
97aa,11 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NPY

Synonyms
CPON, Neuropeptide tyrosine, neuropeptide Y, NPY, PYY4
Background

Neuropeptide Y (NPY) is one of the most abundant peptides in the mammalian central nervous system (CNS). NPY has been linked to several physiological and pathological functions, such as feeding behaviour, memory processing, pain, anxiety, cell proliferation and many other processes in the central and peripheral nervous systems. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. In addition, NPY was suggested as a potential neuroprotective agent in Alzheimer’s disease by counteracting the toxic effect of β-amyloid in an in vitro model.


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