Neuropilin 1 Antibody 2 Publications

Mouse Monoclonal| Catalog number: 60067-1-Ig |CloneNo.: 2H3F6

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
human brain tissue, fetal human brain tissue, human plasma tissue, pig brain tissue

Positive IHC detected in:
human kidney tissue, human gliomas tissue, human kidney tissue, human placenta tissue

Positive IF detected in:
SH-SY5Y cells, human embronic stem cells

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
neuropilin 1

Calculated molecular weight:
103 kDa

Observed molecular weight:
130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NRP1

Synonyms
BDCA4, CD304, DKFZp686A03134, DKFZp781F1414, neuropilin 1, NRP, NRP1, VEGF165R
Background

Neuropilin-1 (NRP1) is a transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.


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