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PAX8-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19120-1-AP

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Con: 16 μg/150 μl

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Tested Applications

Applications:
ELISA
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PAX8-Specific Antibody IHC human ovary tumor tissue 19120-1-AP

Immunohistochemical of paraffin-embedded human ovary tumor using 19120-1-AP(PAX8-Specific antibody) at dilution of 1:50 (under 10x lens)

PAX8-Specific Antibody IHC human ovary tumor tissue 19120-1-AP

Immunohistochemical of paraffin-embedded human ovary tumor using 19120-1-AP(PAX8-Specific antibody) at dilution of 1:50 (under 40x lens)

Species specificity:
human
Recommended dilution:

Protocols

Product-specific protocols

    Standard Protocols

    Product Information

    Source:
    Rabbit
    Purification method:
    Antigen affinity purification
    Isotype:
    IgG
    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

    Immunogen Information

    Immunogen:
    Peptide
    Full name:
    paired box 8
    Calculated molecular weight:
    48 kDa
    Observed molecular weight:
    GenBank accession number:
    NM_013992
    Gene ID (NCBI):
    7849
    Gene symbol
    PAX8
    Synonyms
    paired box 8, Paired box protein Pax 8, PAX8, PAX8-Specific

    Background

    PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells. Mutation of PAX8 will cause congenital hypothyroidism non-goitrous type 2 (CHNG2). This antibody is specific to Pax8. It will not cross react with other PAX members.


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