PAX8-Specific Antibody
PAX8-Specific Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
Cat no : 19120-1-AP
Synonyms
paired box 8, Paired box protein Pax 8, PAX8, PAX8-Specific
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| Sample-dependent, check data in validation data gallery | |
Product Information
19120-1-AP targets PAX8-Specific in ELISA applications and shows reactivity with human samples.
| Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide |
| Full Name | paired box 8 |
| Calculated molecular weight | 48 kDa |
| Observed molecular weight | |
| GenBank accession number | NM_013992 |
| Gene symbol | PAX8 |
| Gene ID (NCBI) | 7849 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20oC. Aliquoting is unnecessary for -20oC storage. |
Background Information
PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells. Mutation of PAX8 will cause congenital hypothyroidism non-goitrous type 2 (CHNG2). This antibody is specific to Pax8. It will not cross react with other PAX members.