PAX8-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19120-1-AP

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Freight/Packing

Con: 16 μg/150 μl

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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
paired box 8

Calculated molecular weight:
48 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PAX8

Synonyms
paired box 8, Paired box protein Pax 8, PAX8, PAX8-Specific
Background

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells. Mutation of PAX8 will cause congenital hypothyroidism non-goitrous type 2 (CHNG2). This antibody is specific to Pax8. It will not cross react with other PAX members.


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